CU-CPTdos2 was used given that site TLR2-antagonist Biological validation To explore the activity of the synthesized and selected compounds 1 to 6 and 9 to 11 on the TLR2 activity, reporter cells overexpressing hTLR2 were used. 7, 10a, 11 Except for 1, all selected compounds decreased TLR2-mediated NF-?B activation in a primary screen (Figure 3A). […]
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